| Date | Age | Event | Bishop | Title | Current Title |
| unknown | 65.0 | Died | Salvador Alepuz † | Archbishop of Sassari, Italy |
| Appointed | Nuno Álvares Pereira † | Bishop of Angra, Portugal |
| 40.4 | Appointed | Renaud de Beaune † | Bishop of Mende, France | Archbishop of Sens, France |
| 40.4 | Ordained Bishop | Renaud de Beaune † | Bishop of Mende, France | Archbishop of Sens, France |
| Born | Gonçalvo (Gonzalo) da Silva † | Redondo, Portugal | Bishop of Ceuta, Spain |
| Ordained Priest | Johann Ertlin † | Priest of Eichstätt, Germany | Auxiliary Bishop of Bamberg, Germany |
| Born | Manuel Esteban Muniera, O. de M. † | Alcaraz | Bishop of Cefalù, Italy |
| Died | Oswald Fischer † | Auxiliary Bishop of Freising, Germany |
| Appointed | Giovanni Francesco Gàmbara † | Bishop of Viterbo e Tuscania, Italy | Cardinal, Bishop of Palestrina, Italy |
| Born | Diego Guevara, O.S.A. † | Baeza, Spain | Bishop of Nueva Caceres, Philippines |
| Died | Giacomo Guidi † | Bishop of Penne-Atri, Italy |
| Appointed | Paolo Odescalchi † | Bishop of Penne-Atri, Italy |
| Born | Pedro de Perea Díaz, O.S.A. † | Briones, Spain | Bishop of Arequipa, Peru |
| 61.4 | Ordained Bishop | Franciscus Sonnius (Van de Velde) † | Bishop of ’s Hertogenbosch (Bois-le-Duc), Netherlands | Bishop of Antwerpen {Antwerp}, Belgium |
| Born | Fernando de Vera y Zuñiga, O.S.A. † | Mérida, Spain | Bishop of Cuzco, Peru |
| Born | Domingo de Villaescusa y Ramírez de Arellano, O.S.H. † | Villaescusa, Spain | Bishop of Yucatán (Mérida), Yucatán, México |
| Resigned | Alfonso de Villalobos † | Bishop of Squillace, Italy | Bishop Emeritus |
| 25 Jan | 48.1 | Ordained Bishop | Stanislaw Karnkowski † | Bishop of Włocławek, Poland | Archbishop of Gniezno, Poland |
| 1 Feb | | Died | Bartolomé Torres † | Bishop of Islas Canarias {Canary Islands}, Spain |
| 12 Feb | 94.1 | Died | Rembert von Kerssenbrock † | Bishop of Paderborn, Germany |
| 22 Feb | 38.8 | Appointed | Johann Graf von Hoya zu Stolzenau † | Bishop of Paderborn, Germany | Bishop of Münster, Germany |
| 29 Feb | 85.2 | Died | Fernando de Loaces (Loazes), O.P. † | Archbishop of Valencia, Spain |
| 24 Mar | 54.6 | Elevated to Cardinal | Diego Espinosa Arévalo † | Cardinal, Bishop of Sigüenza, Spain |
| 5 Apr | | Born | Maffeo Barberini † | Florence | Pope (Roma {Rome}, Italy) |
| 17 Apr | 58.3 | Ordained Bishop | Jakob von Eltz † | Archbishop of Trier, Germany |
| 30 Apr | 68.3 | Died | Ludovico Simonetta † | Cardinal, Bishop of Pesaro, Italy |
| 4 May | | Died | Guillaume Viole † | Bishop of Paris, France |
| 5 May | | Born | Alessandro d'Este † | Ferrara | Cardinal, Bishop of Reggio Emilia, Italy |
| 8 May | 35.4 | Appointed | Pierre de Gondi † | Bishop of Paris, France | Cardinal, Bishop Emeritus |
| 14 May | 50.7 | Appointed | Antoine Perrenot de Granvella † | Cardinal-Priest of S. Prisca | Cardinal, Archbishop of Besançon, France |
| 31 May | | Died | Wolfgang Westermeyer † | Auxiliary Bishop of Mainz, Germany |
| 2 Jun | | Appointed | Francisco Andrés de Carvajal, O.F.M. † | Bishop of Puerto Rico (Porto Rico) | Archbishop of Santo Domingo, Dominican Republic |
| Appointed | Pedro Gómez (Fernández) de Córdoba, O.S.H. † | Bishop of León en Nicaragua | Bishop of Guatemala (Santiago de Guatemala), Guatemala |
| 1 Jul | | Born | Philipp Sigismund Herzog von Braunschweig-Lüneburg † | | Bishop-Elect of Osnabrück, Germany |
| 5 Jul | 54.8 | Appointed | Diego Espinosa Arévalo † | Cardinal, Bishop of Sigüenza, Spain |
| 23 Jul | 38.6 | Appointed | Amador Arrais (de Mondoza), O. Carm. † | Auxiliary Bishop of Évora, Portugal | Bishop Emeritus of Portalegre, Portugal |
| Appointed | Jorge de Ataíde † | Bishop of Viseu, Portugal |
| 57.6 | Appointed | Bl. Paul Burali d'Arezzo, C.R. † | Bishop of Piacenza, Italy | Cardinal, Archbishop of Napoli {Naples}, Italy |
| 57.6 | Appointed | Gaspar Cervantes de Gaete † | Cardinal, Archbishop of Tarragona, Spain |
| Appointed | Gonzalo Herrera Olivares † | Auxiliary Bishop of Burgos, Spain |
| Appointed | Juan Segría † | Archbishop of Sassari, Italy | Archbishop of Palermo, Italy |
| Appointed | Juan Vázquez Coronado de Sayás † | Bishop of Acerra, Italy |
| 25 Jul | | Ordained Bishop | Gonzalo Herrera Olivares † | Auxiliary Bishop of Burgos, Spain |
| 1 Aug | 57.6 | Ordained Bishop | Bl. Paul Burali d'Arezzo, C.R. † | Bishop of Piacenza, Italy | Cardinal, Archbishop of Napoli {Naples}, Italy |
| 2 Aug | 43.6 | Appointed | Francesco Bossi † | Bishop of Gravina, Italy | Bishop of Novara, Italy |
| 7 Sep | | Appointed | Antonio Rodríguez de Pazos y Figueroa † | Bishop of Patti, Italy | Bishop of Córdoba, Spain |
| 17 Sep | | Appointed | Juan de Arzolaras (Alzóloras), O.S.H. † | Archbishop (Personal Title) of Islas Canarias {Canary Islands}, Spain | Bishop |
| 48.7 | Installed | Antonio de San Miguel Avendaño y Paz, O.F.M. † | Bishop of Concepción, Chile | Bishop of Quito, Ecuador |
| 28 Oct | | Died | Girolamo Gallarati † | Bishop of Alessandria (della Paglia), Italy |
| Born | Juan (de la Serna) Sánchez Alonso de Guevara † | Cabeza del Buey | Bishop of Lugo, Spain |
| Nov | | Born | Richard Smith † | Hanworth | Vicar Apostolic Emeritus of England, Great Britain |
| 3 Nov | | Born | Juan Esteban (Giovanni Stefano) Ferrero, O. Cist. † | Biella | Bishop of Vercelli, Italy |
| 6 Nov | 39.6 | Confirmed | Johann Graf von Hoya zu Stolzenau † | Bishop of Paderborn, Germany | Bishop of Münster, Germany |
| 20 Nov | | Born | Bernardo de Valbuena y Villanueva † | Valdepeñas, Spain | Bishop of Puerto Rico (Porto Rico) |
| 3 Dec | 36.7 | Appointed | St. Juan de Ribera † | Archbishop of Valencia, Spain |
| Appointed | Diego de Simancas † | Bishop of Badajoz, Spain | Bishop of Zamora, Spain |
| 8 Dec | | Ordained Bishop | Antonio Rodríguez de Pazos y Figueroa † | Bishop of Patti, Italy | Bishop of Córdoba, Spain |
| 10 Dec | | Appointed | Andrés Pérez † | Bishop of Ciudad Rodrigo, Spain |
| 13 Dec | | Appointed | Miguel Maigues, O.S.A. † | Bishop of Ales e Terralba, Italy |
| 14 Dec | | Died | Bartolomé Sebastián de Aroitia † | Archbishop of Tarragona, Spain |
| 23 Dec | | Died | Friedrich Graf zu Wied † | Former Archbishop-Elect of Köln {Cologne}, Germany |