| Date | Age | Bishop | Title |
|---|
| unknown | | Luca Castellini † | Bishop of Catanzaro, Italy |
| unknown | | Alvaro Mendoza, O.F.M. † | Bishop of Jaca, Spain |
| unknown | 63.0 | Pedro de Perea Díaz, O.S.A. † | Bishop of Arequipa, Peru |
| unknown | | Marsilio Peruzzi † | Archbishop of Chieti, Italy |
| unknown | | Pedro de Valencia † | Bishop of La Paz, Bolivia |
| 21 Jan | 65.1 | Diego Guzmán de Haros † | Cardinal, Archbishop of Sevilla {Seville}, Spain |
| 28 Jan | | Gonzalo Hernandez y Hermosillo y Gonzalez, O.S.A. † | Bishop of Durango, México |
| 8 Mar | | Juan Portocarrero, O.F.M. † | Bishop of Almería, Spain |
| 17 Mar | 73.2 | Juan Venido Castilla, O.F.M. † | Bishop of Orense, Spain |
| 28 Mar | 64.4 | José González Díez, O.P. † | Archbishop of Burgos, Spain |
| 18 Apr | | Cosimo de' Bardi † | Archbishop of Firenze {Florence}, Italy |
| 7 May | | Giovanni Tiepolo † | Patriarch of Venezia {Venice}, Italy |
| 9 Jun | | Antonio Viedma Chaves, O.P. † | Bishop of Almería, Spain |
| 16 Jun | | Tomás Espinosa † | Auxiliary Bishop of Valencia, Spain |
| 5 Jul | 56.5 | Agustin de Hinojosa y Montalvo, O.F.M. † | Bishop of León en Nicaragua |
| 11 Jul | | Geronimo de Gouvea, O.F.M. † | Bishop Emeritus of Ceuta, Spain |
| 16 Jul | 47.8 | Philipp Adolf von Ehrenberg † | Bishop of Würzburg, Germany |
| 8 Aug | 61.6 | Juan Pérez de la Serna † | Bishop of Zamora, Spain |
| 28 Aug | | Marino Zorzi † | Bishop of Brescia, Italy |
| 21 Sep | 67.1 | Federico Borromeo (Sr.) † | Cardinal, Archbishop of Milano {Milan}, Italy |
| 4 Oct | | Agostino Priuli † | Bishop of Bergamo, Italy |
| 14 Oct | 63.8 | Manuel Esteban Muniera, O. de M. † | Bishop of Cefalù, Italy |
| 14 Oct | 66.8 | Pedro Moya Arjona † | Bishop of Tui, Spain |
| 8 Nov | | Francisco Márquez Gaceta † | Bishop of Avila, Spain |
| 28 Nov | 78.9 | Martín Terrer Valenzuela, O.S.A. † | Archbishop of Zaragoza, Spain |
| 31 Dec | | Pedro Herrera Suárez, O.P. † | Bishop of Tarazona, Spain |
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