| Date | Age | Bishop | Title |
|---|
| unknown | | Martim Afonso Mexia (de Tovar) † | Bishop of Coimbra, Portugal |
| unknown | | Juan Cuenca † | Bishop of Cádiz, Spain |
| unknown | 55.0 | Diego Guevara, O.S.A. † | Bishop of Nueva Caceres, Philippines |
| unknown | | Leonardo Mocenigo † | Bishop of Ceneda, Italy |
| unknown | | António de Santa Maria † | Bishop of Leiria, Portugal |
| unknown | | Jerónimo Tiedra Méndez, O.P. † | Archbishop of La Plata o Charcas, Bolivia |
| 1 Mar | 78.2 | Francisco López de Mendoza † | Bishop of Sigüenza, Spain |
| 19 Mar | 54.7 | Philipp Sigismund Herzog von Braunschweig-Lüneburg † | Bishop-Elect of Osnabrück, Germany |
| 8 Jul | 69.5 | Alessandro Ludovisi † | Pope (Roma {Rome}, Italy) |
| 12 Aug | 45.6 | Stefano Pignatelli † | Cardinal, Cardinal-Priest of S. Maria in Via |
| 19 Aug | 53.6 | Giacomo Serra † | Cardinal, Cardinal-Priest of S. Maria della Pace |
| 24 Aug | 82.6 | Antonio Maria Sauli † | Cardinal, Bishop of Ostia (-Velletri), Italy |
| 1 Sep | 49.7 | Marco Antonio Gozzadini † | Cardinal, Bishop of Faenza, Italy |
| 6 Sep | 56.7 | Francesco Sacrati † | Cardinal, Bishop of Cesena, Italy |
| 17 Sep | 72.0 | Lothar von Metternich † | Archbishop of Trier, Germany |
| 30 Sep | 46.7 | Cesare Gherardi † | Cardinal, Bishop of Camerino, Italy |
| 13 Oct | | Juan Alvarez Zapata, O. Cist. † | Bishop of Solsona, Spain |
| Nov | | Juan Molina Alvarez † | Bishop of León, Spain |
| 20 Dec | 89.6 | Pedro Castro Quiñones † | Archbishop of Sevilla {Seville}, Spain |
| 25 Dec | 59.0 | Lucio Sanseverino † | Cardinal, Archbishop of Salerno, Italy |
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