| Date | Age | Bishop | Title |
|---|
| unknown | | Juan Francisco de Aguirre † | Bishop of Tropea, Italy |
| unknown | | Cesare Gesualdo † | Bishop of Mottola (Motula), Italy |
| unknown | | Diego Gilberto Nogueras † | Bishop of Alife, Italy |
| 21 Jun | | Georg Riedl † | Auxiliary Bishop of Regensburg, Germany |
| 2 Jul | | Pedro Maldonado, O.F.M. † | Bishop of Mondoñedo, Spain |
| 30 Jul | 59.5 | Honorato Juan † | Bishop of Osma, Spain |
| 31 Jul | 91.7 | Bartolomé de las Casas (Casaus), O.P. † | Bishop Emeritus of Chiapas (Ciudad Real de Chiapas), Chiapas, México |
| 5 Aug | 61.7 | Martín Pérez de Ayala † | Archbishop of Valencia, Spain |
| 16 Aug | | Jerónimo Velasco † | Bishop of Oviedo, Spain |
| 13 Sep | 27.8 | Sigismund Markgraf von Brandenburg † | Former Archbishop-Elect of Magdeburg, Germany |
| 26 Sep | | Sebastiano Gualterio † | Bishop of Viterbo e Tuscania, Italy |
| 22 Nov | | Domingo Cubels † | Bishop of Malta |
| 28 Nov | 58.2 | Francisco Mendoza Bobadilla † | Cardinal, Archbishop of Burgos, Spain |
| Dec | | Luís de la Fuente (Fuentes) † | Bishop of León en Nicaragua |
| 4 Dec | 72.0 | Georg Herzog von Braunschweig-Lüneburg † | Archbishop-Elect of Bremen(-Hamberg), Germany |
| 9 Dec | 83.9 | Fernando Valdés † | Archbishop of Sevilla {Seville}, Spain |
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