| Date | Age | Bishop | Title |
| unknown | | Giovanni Giacomo Castiglione † | Archbishop of Bari (-Canosa), Italy |
| unknown | | Alfonso d’Aragona † | Bishop of Tortosa, Spain |
| unknown | | Bernardino da Bologna † | Archbishop of Messina, Italy |
| unknown | | Battista Del Bufalo † | Bishop of Aquino, Italy |
| unknown | | Albertino della Rovere † | Bishop of Pesaro, Italy |
| unknown | | Giorgio Maccafano de’ Pireto † | Bishop of Sarno, Italy |
| unknown | | Tommaso Malombra † | Bishop of Stagno (Ston), Croatia |
| unknown | | Giovanni Maria Sforza † | Archbishop of Genova, Italy |
| Feb | | Pedro López Ayala † | Bishop of Islas Canarias {Canary Islands}, Spain |
| 4 Feb | 52.1 | Philipp von Rosenberg † | Bishop of Speyer, Germany |
| 9 Feb | | George Hepburn † | Bishop of The Isles (Sodor), Scotland, Great Britain |
| 11 Feb | | Dafydd (David) ab Owain (Owen), O. Cist. † | Bishop of Saint Asaph, Wales, Great Britain |
| 14 Feb | | Juan de Enguera, O.P. † | Bishop of Tortosa, Spain |
| 21 Feb | 59.2 | Giuliano della Rovere † | Pope (Roma {Rome}, Italy) |
| 8 Apr | 46.3 | Cosimo de’ Pazzi † | Archbishop of Firenze {Florence}, Italy |
| 31 Jul | | Leonardo Marchesi † | Bishop of Albenga, Italy |
| 3 Aug | 49.6 | Ernst Herzog von Sachsen † | Archbishop of Magdeburg, Germany |
| 9 Sep | 20.7 | Alexander Stewart † | Archbishop-Elect of Saint Andrews, Scotland, Great Britain |
| 20 Sep | | Wincenty Przerębski † | Bishop of Włocławek (Kujawy, Kalisze), Poland |
| 9 Nov | 53.9 | Robert Guibé † | Cardinal, Administrator of Vannes, France |